Cobalt‐Catalyzed Multi‐Substituted Alkene Synthesis from 1,3‐Dithiolanes and Grignard Reagents

Abstract The cobalt‐catalyzed reaction between 1,3‐dithiolanes and Grignard reagents, for the efficient synthesis of multi‐substituted alkene products, is described. method was applicable to a variety benzylic dithiolane substrates, affording di‐, tri‐, tetra‐substituted 1,1‐diaryl products in good excellent yields. use reagents with aryl aldehyde‐derived enabled access natural product‐derived stilbene architectures exquisite E selectivity. operational simplicity, low catalyst loadings, scalability demonstrate general utility method.